POTENSI FITOKIMIA DAN TOKSISITAS EKSTRAK DAUN JABOTICABA (Plinia cauliflora (Mart.) Kausel) HASIL BUDIDAYA DI INDONESIA

Muhammad Khabib Bullah, Bekti Widiharto, Fawwaz Muhammad Fauzi

Abstract


Pendahuluan: Jaboticaba (Plinia cauliflora (Mart.) Kausel) merupakan jenis tumbuhan yang berasal dari benua Amerika, khususnya Brazil dan saat ini mulai banyak dibudidayakan di Indonesia sebagai daya tarik ekowisata. Peningkatan popularitasnya perlu diimbangi dengan eksplorasi potensi pemanfaatannya dari berbagai aspek, salah satunya adalah manfaat kesehatan. Tujuan: Penelitian ini bermaksud mengungkap senyawa metabolit sekunder dan potensi toksisitas Daun P. cauliflora dari Majalengka, Jawa Barat. Metode: Daun P. cauliflora diekstraksi dengan metode maserasi bertingkat dengan pelarut berbeda, yaitu n-heksana, etil asetat dan etanol. Ketiga ekstrak yang didapatkan dilakukan skrining fitokimia secara kualitatif dengan uji reagen dan diuji toksisitasnya dengan metode BSLT. Hasil: Ketiga ekstrak secara umum menunjukkan keberadaan senyawa fenolik, flavonoid, alkaloid, saponin, steroid/triterpenoid, kecuali flavonoid yang tidak terdeteksi pada ekstrak n-heksana. Ekstrak n-heksana, etil asetat dan etanol menunjukkan nilai LC50 berturut-turut sebesar 108,33 ppm, 1216,09 ppm dan 2308,09 ppm. Kesimpulan: Ekstrak mengandung senyawa metabolit sekunder yang dapat berkontribusi pada toksisitas. Toksisitas ekstrak n-heksana tergolong toksik sedang, sedangkan ekstrak etil asetat dan etanol tergolong tidak toksik.

Keywords


Daun Jaboticaba (Plinia cauliflora); Toksisitas; Fitokimia

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References


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DOI: https://doi.org/10.33085/jdf.v9i3.6491

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